The Daniels Hotel is the safe house where Bullitt is guarding Johnny Ross. It was at the time of the movie the Kennedy Hotel located at 226 Embarcadero near the corner of Howard and the Embarcadero.
Then ... Bullitt and partner Det. Sgt. Carl Stanton (Carl Reidel) leave the hotel and cross Howard Street where it met the Embarcadero. Piers 18, 20 and 22 recede towards the Bay Bridge.
Then ... The night view shows the hotel and the ill-fated double-decker freeway which passed behind the hotel and along the Embarcadero to Broadway. The freeway was severely damaged in the 1989 earthquake and subsequently removed, along with this city block.
The view below from the window of Ross's room at the rear of the hotel shows the freeway passing close by. The same hotel is seen near the end of the car chase ten years earlier in the movie 'The Lineup', viewed from the freeway - see it here.
... and Now, the same view from in front of the hotel site is no longer blocked by the demolished piers.