D.O.A. - Hotel
Bigelow stayed at the historic century-old St. Francis Hotel at 335 Powell Street on Union Square.
Then ... The movie view from outside the main entrance looks north up Powell Street with Union Square off to the right (click image to enlarge).
... and Now, the background buildings along Post Street have been rebuilt but the iconic cable cars still clang their way up and down the hill. Note the same awning pillars and the row of globed lampstands still there along the sidewalk in front of the hotel.